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Aripiprazole cardiosafety: Is it overestimated?
Aripiprazole is a third‐generation atypical (novel) antipsychotic, dihydroquinolinone, famously known as dopamine stabilizer, uniquely D2/D3 partial agonist, and 5HT1A agonist. It is a Food and Drug Administration‐approved drug for schizophrenia, bipolar mood disorder, augmentation in unipolar depression, irritability in autism, and Tourette syndrome in pediatric age group. It is lauded for bei...
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Real-world scenes are complex but lawful: blenders are more likely to be found in kitchens than beaches, and elephants are not generally found inside homes. Research over the past 40years has demonstrated that contextual associations influence object recognition, change eye movement distributions, and modulate brain activity. However, the majority of these studies choose object-scene pairs from...
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Oxygen is recognized as a structuring factor of metazoan communities in marine sediments. The importance of oxygen as a controlling factor on meiofauna (32 µm-1 mm in size) respiration rates is however less clear. Typically, respiration rates are measured under oxic conditions, after which these rates are used in food web studies to quantify the role of meiofauna in sediment carbon turnover. Se...
متن کاملPolicy relevance of Bayesian statistics overestimated?
OBJECTIVES The observed posterior probability distributions regarding the benefits of surgery for otitis media with effusion (OME) with expected probability distributions, using Bayes' theorem are compared. METHODS Postal questionnaires were used to assess prior and posterior probability distributions among ear-nose-throat (ENT) surgeons in the Netherlands. RESULTS In their prior probabilit...
متن کاملHas the burden of depression been overestimated?
OBJECTIVE To investigate whether high estimates of the burden of depression could be attributed to an overestimation of disability weights (reflecting more severe disability). METHODS We derived disability weights that were tailored to prevalence data. Empirical disability data from a Dutch community survey was used to describe three classes of severity of depression and their proportional pr...
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ژورنال
عنوان ژورنال: BMJ
سال: 1995
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.311.7016.1372